What is Quercetin?

Quercetin is a flavonoid abundant in fruits, vegetables, and grains, renowned for its antioxidant and anti-inflammatory properties. In skincare, quercetin exhibits potent anti-aging effects by scavenging free radicals, reducing oxidative stress, and shielding against UV-induced damage. It promotes collagen synthesis, enhances skin elasticity, and diminishes the appearance of fine lines and wrinkles. Additionally, quercetin inhibits enzymes involved in collagen breakdown, helping to maintain youthful skin structure and resilience, resulting in a smoother, rejuvenated complexion.

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Quercetin

What are the benefits of Quercetin for my hair?

Quercetin is a flavonoid compound found in various fruits, vegetables, and plants. While its direct effects on hair health are not as extensively studied as some other nutrients, there are several potential benefits of quercetin for hair:

Antioxidant Protection: Quercetin is a potent antioxidant that helps neutralize free radicals, which can cause oxidative stress and damage to hair follicles. By reducing oxidative damage, quercetin may help maintain a healthy scalp environment conducive to optimal hair growth.

Anti-inflammatory Properties: Quercetin possesses anti-inflammatory properties that can help soothe and calm an irritated scalp. Inflammation of the scalp can disrupt the hair growth cycle and contribute to hair loss or thinning. Quercetin's anti-inflammatory effects may help alleviate scalp conditions and promote healthier hair growth.

Supports Circulation: Some research suggests that quercetin may help improve blood circulation by dilating blood vessels. Better circulation in the scalp ensures that essential nutrients and oxygen reach the hair follicles, promoting healthier hair growth and scalp health.

Inhibits DHT Production: Quercetin has been shown to inhibit the activity of 5-alpha-reductase, an enzyme that converts testosterone into dihydrotestosterone (DHT). Excessive levels of DHT can contribute to hair loss and thinning in both men and women. By reducing DHT levels, quercetin may help prevent hair loss and promote hair retention.

Stimulates Hair Follicles: Quercetin may help stimulate hair follicles and promote the growth of new hair. While more research is needed to fully understand its mechanisms, some studies suggest that quercetin may have a positive effect on hair growth when applied topically or consumed orally.

Protects Against Environmental Damage: Quercetin's antioxidant properties help protect the hair and scalp from damage caused by UV radiation, pollution, and other environmental stressors. This protection can help prevent dryness, brittleness, and damage to the hair shaft, keeping the hair looking healthy and vibrant.

Quercetin’s antioxidant, anti-inflammatory, and potential DHT-blocking properties make it a promising compound for supporting overall scalp and hair health. Incorporating quercetin-rich foods such as apples, onions, berries, and leafy greens into your diet may provide some benefits for hair health. Additionally, topical treatments containing quercetin may offer targeted support for scalp and hair conditions.

Is Quercetin Safe?

Quercetin is safe on the hair and scalp when used at the recommended levels.

Is Quercetin organic?

Quercetin is an organic, natural, plant compound found in many plants and vegetables.

References

Anand David, A. V., Arulmoli, R., & Parasuraman, S. (2016). Overviews of Biological Importance of Quercetin: A Bioactive Flavonoid. Pharmacognosy Reviews, 10(20), 84. https://doi.org/10.4103/0973-7847.194044

Casagrande, R., Georgetti, S. R., Verri, W. A., Dorta, D. J., dos Santos, A. C., & Fonseca, M. J. V. (2006). Protective effect of topical formulations containing quercetin against UVB-induced oxidative stress in hairless mice. Journal of Photochemistry and Photobiology B: Biology, 84(1), 21–27. https://doi.org/10.1016/J.JPHOTOBIOL.2006.01.006

Comalada, M., Camuesco, D., Sierra, S., Ballester, I., Xaus, J., Gálvez, J., & Zarzuelo, A. (2005). In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-κB pathway. European Journal of Immunology, 35(2), 584–592. https://doi.org/10.1002/eji.200425778

Costa, L. G., Garrick, J. M., Roquè, P. J., & Pellacani, C. (2016). Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More. Oxidative Medicine and Cellular Longevity, 2016. https://doi.org/10.1155/2016/2986796

Csekes, E., & Račková, L. (2021). Skin Aging, Cellular Senescence and Natural Polyphenols. International Journal of Molecular Sciences, 22(23). https://doi.org/10.3390/ijms222312641

Domaszewska-Szostek, A., Puzianowska-Kuźnicka, M., & Kuryłowicz, A. (2021). Flavonoids in Skin Senescence Prevention and Treatment. International Journal of Molecular Sciences, 22(13), 6814. https://doi.org/10.3390/IJMS22136814

Hatahet, T., Morille, M., Hommoss, A., Devoisselle, J. M. M., Müller, R. H. H., & Bégu, S. (2016). Quercetin topical application, from conventional dosage forms to nanodosage forms. European Journal of Pharmaceutics and Biopharmaceutics, 108, 41–53. https://doi.org/10.1016/J.EJPB.2016.08.011

Kitagawa, S., Tanaka, Y., Tanaka, M., Endo, K., & Yoshii, A. (2009). Enhanced skin delivery of quercetin by microemulsion. The Journal of Pharmacy and Pharmacology, 61(7), 855–860. https://doi.org/10.1211/JPP/61.07.0003

Lee, M., McGeer, E. G., & McGeer, P. L. (2016). Quercetin, not caffeine, is a major neuroprotective component in coffee. Neurobiology of Aging, 46, 113–123. https://doi.org/10.1016/J.NEUROBIOLAGING.2016.06.015

Remigante, A., Spinelli, S., Basile, N., Caruso, D., Falliti, G., Dossena, S., Marino, A., & Morabito, R. (2022). Oxidation Stress as a Mechanism of Aging in Human Erythrocytes: Protective Effect of Quercetin. International Journal of Molecular Sciences, 23(14). https://doi.org/10.3390/IJMS23147781

Takekoshi, S., Matsuzaki, K., & Kitatani, K. (2013). Quercetin stimulates melanogenesis in hair follicle melanocyte of the mouse. The Tokai Journal of Experimental and Clinical Medicine, 38(4), 129–134. https://europepmc.org/article/med/24318284

Vicentini, F. T. M. C., He, T., Shao, Y., Fonseca, M. J. V., Verri, W. A., Fisher, G. J., & Xu, Y. (2011). Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway. Journal of Dermatological Science, 61(3), 162–168. https://doi.org/10.1016/J.JDERMSCI.2011.01.002

Wadhwa, K., Kadian, V., Puri, V., Bhardwaj, B. Y., Sharma, A., Pahwa, R., Rao, R., Gupta, M., & Singh, I. (2022). New insights into quercetin nanoformulations for topical delivery. Phytomedicine Plus, 2(2), 100257. https://doi.org/10.1016/J.PHYPLU.2022.100257

Zhao, Q., Zheng, Y., Zhao, D., Zhao, L., Geng, L., Ma, S., Cai, Y., Liu, C., Yan, Y., Belmonte, J. C. I., Wang, S., Zhang, W., Liu, G.-H., & Qu, J. (2022). Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration. Protein & Cell, XX, 1–18. https://doi.org/10.1093/PROCEL/PWAC062